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CANCER

GENETIC CANCER RISK

Female Breast

High Risk 

Gastric

High Risk

Colorectal

Elevated Risk

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CANCER TYPE

AGE RANGE

CANCER RISK

RISK FOR GENERAL POPULATION

Gastric (male)

To age 80

67%-70%

0.6%

Gastric (female)

To age 80

56%-83%

0.6%

Female Breast

To age 50

10%

1.9%

To age 80

39%-52%

10.2%

Colorectal

To age 80

Possibly elevated risk

3.0%

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CANCER TYPE

PROCEDURE

AGE TO BEGIN

FREQUENCY

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Gastrectomy

18 to 40 years, or individualized to a younger age if a relative was diagnosed under age 25

NA

Baseline endoscopy prior to gastrectomy. Upper endoscopies with random biopsies may be appropriate for patients delaying or declining gastrectomy.

Individualized

Every 6 to 12 months

Consider testing and treating for Helicobacter pylori infection if present.

Individualized

NA

Female Breast

Breast awareness - Women should be familiar with their breasts and promptly report changes to their healthcare provider. Periodic, consistent breast self-examination (BSE) may facilitate breast awareness.

18 years

NA

Clinical breast examination

25 years

Every 6 months

Mammography with consideration of tomosynthesis and consideration of breast MRI with contrast

30 to 35 years

Annually

Colorectal 

Consider colonoscopy for patients with a family history of colorectal cancer.

Individualized

Individualized

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