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EGFR

Associated Syndrome

EGFR-associated Cancer Risk

Core Cancer Risk(s)

Non-small cell Lung Cancer

Inheritance 

Autosomal Dominant 

Prevalence

Unknown

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CANCER

GENETIC CANCER RISK

Lung

Elevated Risk

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CANCER TYPE

AGE RANGE

CANCER RISK

RISK FOR GENERAL POPULATION 

Lung

To age 80

Elevated Risk

4.3%

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CANCER TYPE

PROCEDURE

AGE TO BEGIN

FREQUENCY

Lung

Currently there are no specific medical management guidelines for lung cancer risk in mutation carriers. However, the increased risk may warrant consideration of individualized screening with low dose chest CT scans, as has been considered for individuals at increased risk due to smoking.

NA

NA

For Patients with a Cancer Diagnosis

For patients with a diagnosis of lung cancer, the presence of this EGFR gene mutation may impact decisions about the choice of drugs for therapy.

NA

NA

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