MITF

Associated Syndrome

MITF-related Cancer Risk

Core Cancer Risk(s)

Melanoma

Inheritance 

Autosomal Dominant 

Prevalence

unkno

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CANCER

GENETIC CANCER RISK

Skin

Elevated Risk

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CANCER TYPE

PROCEDURE

AGE TO BEGIN

RISK FOR GENERAL POPULATION *

Melanoma

To age 80

Elevated Risk

1.7%

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CANCER TYPE

PROCEDURE

AGE TO BEGIN

FREQUENCY

Melanoma

Currently there are no specific medical management recommendations for melanoma risk in mutation carriers. However, the increased risk for melanoma warrants consideration of risk-reduction strategies, including frequent self-examination of the skin, consideration of clinical skin examinations, and minimizing exposure to the sun and other sources of UV radiation.

Individualized

NA