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Hereditary Cancer Syndromes > MUTYH
CANCER TYPE
PROCEDURE
AGE TO BEGIN
FREQUENCY
Colorectal
To age 80
43%-100%
3.0%
Small Bowel
To age 80
5%
0.2%
CANCER TYPE
PROCEDURE
AGE TO BEGIN
FREQUENCY
Colorectal
To age 80
3.4% to 10%
3.0%
CANCER TYPE
PROCEDURE
AGE TO BEGIN
FREQUENCY
Colorectal
Colonoscopy
25 to 30 years
Every 1 to 2 years
Colorectal surgical evaluation and counseling.
Based on cancer diagnosis and/or polyp number, size and histology
NA
Small Bowel
Consider upper endoscopy, including complete visualization of the ampulla of Vater
30 to 35 years
Every 4 years
CANCER TYPE
PROCEDURE
AGE TO BEGIN
FREQUENCY
Colorectal
Currently there are no medical management guidelines for colorectal cancer risk in patients with a single MUTYH mutation unless colorectal cancer has been diagnosed in a first-degree relative
NA
NA
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