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CANCER

GENETIC CANCER RISK

Colorectal

High Risk

Other

High Risk

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CANCER

GENETIC CANCER RISK

Colorectal

Elevated Risk

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CANCER TYPE

PROCEDURE

AGE TO BEGIN

FREQUENCY

Colorectal

To age 80

43%-100%

3.0%

Small Bowel

To age 80

5%

0.2%

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CANCER TYPE

PROCEDURE

AGE TO BEGIN

FREQUENCY

Colorectal

To age 80

3.4% to 10%

3.0%

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CANCER TYPE

PROCEDURE

AGE TO BEGIN

FREQUENCY

Colorectal

Colonoscopy

25 to 30 years

Every 1 to 2 years

Colorectal surgical evaluation and counseling.

Based on cancer diagnosis and/or polyp number, size and histology

NA

Small Bowel

Consider upper endoscopy, including complete visualization of the ampulla of Vater

30 to 35 years

Every 4 years

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CANCER TYPE

PROCEDURE

AGE TO BEGIN

FREQUENCY

Colorectal

Currently there are no medical management guidelines for colorectal cancer risk in patients with a single MUTYH mutation unless colorectal cancer has been diagnosed in a first-degree relative

NA

NA

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