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CANCER

GENETIC CANCER RISK

Colorectal

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Female Breast

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CANCER TYPE

AGE RANGE

CANCER RISK

RISK FOR GENERAL POPULATION

Colorectal

To age 80

Elevated risk

3.0%

Female Breast

To age 80

Elevated risk

10.2%

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CANCER TYPE

PROCEDURE

AGE TO BEGIN

FREQUENCY

Colorectal

Colonoscopy

25 to 30 years

Every 2 to 3 years

Colorectal surgical evaluation and counseling.

Based on cancer diagnosis and/or polyp number, size and histology

NA

Female Breast

NA

NA

Currently there are no specific medical management guidelines for female breast cancer risk in biallelic mutation carriers. However, the possibility of an increased risk for breast cancer warrants consideration of individualized breast cancer risk-reduction strategies, such as the modification of standard population screening recommendations by starting screening at younger ages and/or performing screenings at greater frequency