Hereditary Cancer Syndromes > POLD1, POLE, MSH3
GENETIC CANCER RISK
RISK FOR GENERAL POPULATION
To age 80
AGE TO BEGIN
25 to 30 years
Every 2 to 3 years
Colorectal surgical evaluation and counseling.
Based on cancer diagnosis and/or polyp number, size and histology
Carrier Status for MSH3-associated Cancer Risk
Individuals with a mutation in only one copy of the MSH3 gene (a monoallelic mutation) are not believed to have any increased risk for cancer over people in the general population.