top of page

Hereditary Cancer Syndromes > POLD1, POLE, MSH3



CANCER
GENETIC CANCER RISK
Colorectal
High Risk

CANCER TYPE
AGE RANGE
CANCER RISK
RISK FOR GENERAL POPULATION
Colorectal
To age 80
Elevated risk
2.8%

CANCER TYPE
PROCEDURE
AGE TO BEGIN
FREQUENCY
Colorectal
Colonoscopy
25 to 30 years
Every 2 to 3 years
Colorectal surgical evaluation and counseling.
Based on cancer diagnosis and/or polyp number, size and histology
NA
Carrier Status for MSH3-associated Cancer Risk
-
Individuals with a mutation in only one copy of the MSH3 gene (a monoallelic mutation) are not believed to have any increased risk for cancer over people in the general population.
bottom of page